Description

KPV Peptide — 10 mg

KPV, also known as Lys-Pro-Val, is a synthetic tripeptide composed of lysine, proline, and valine. It represents the C-terminal sequence of alpha-melanocyte-stimulating hormone (α-MSH) and has been studied in laboratory and preclinical models involving inflammatory signaling, intestinal epithelial responses, immune-cell activity, and cellular communication.

Supplied as a 10 mg lyophilized research peptide for controlled laboratory investigations.

For laboratory research use only. Not for human or animal consumption.

OVERVIEW

KPV is a short-chain tripeptide consisting of the amino acid sequence Lys-Pro-Val. It corresponds to amino acids 11–13 of α-MSH and has been investigated for biological activity separate from the full-length hormone.

Laboratory research has examined KPV in relation to inflammatory signaling pathways, including NF-κB and MAP kinase activity, cytokine expression, epithelial-cell responses, and peptide transport through PepT1.

Preclinical studies have also explored KPV in cellular and animal models involving intestinal inflammation, mucosal responses, immune signaling, and tissue-protective mechanisms. These findings remain investigational and do not establish KPV as an approved treatment or therapeutic product.

PRODUCT SPECIFICATIONS

Compound: KPV / Lys-Pro-Val
Sequence: Lys-Pro-Val
Full Sequence: H-Lys-Pro-Val-OH
Quantity: 10 mg
Form: Lyophilized powder
Molecular Formula: C16H30N4O4
Molecular Weight: 342.43 g/mol
CAS: 67727-97-3
Storage: 2–8°C recommended; protect from light and moisture
Purity: Refer to the current batch Certificate of Analysis

Specifications should be verified against the applicable batch CoA. Modified forms such as Ac-KPV, KPV-NH₂, or salt formulations may have different molecular weights, formulas, and CAS numbers.

RESEARCH APPLICATIONS

• Inflammatory signaling research
• NF-κB pathway investigations
• MAP kinase pathway studies
• Cytokine-expression research
• Intestinal epithelial-cell models
• PepT1 transport studies
• Immune-cell response research
• Mucosal barrier and tissue-response models
• Peptide signaling investigations
• Oxidative-stress and cellular-response studies

RESEARCH BACKGROUND

KPV is derived from the C-terminal region of α-MSH and has been studied as a biologically active tripeptide in its own right. Unlike the complete α-MSH molecule, KPV does not contain the full sequence associated with melanocortin receptor-mediated pigmentation.

In laboratory studies, KPV has been investigated for its effects on inflammatory signaling in intestinal epithelial and immune-cell models. Research has reported interactions involving PepT1-mediated cellular uptake, NF-κB activation, MAP kinase signaling, and the expression of inflammatory cytokines.

Additional preclinical research has explored KPV in mouse models of experimentally induced intestinal inflammation and in delivery systems designed to target intestinal tissues. These studies are useful for understanding peptide transport, cellular signaling, and inflammatory-response mechanisms.

Results from cell and animal models should not be interpreted as evidence of safety, efficacy, dosage, or approved therapeutic use in humans.

RESEARCH USE ONLY

This product is intended strictly for qualified laboratory research.

Not for human consumption. Not for veterinary use. Not for injection. Not for therapeutic or diagnostic applications. Not intended to diagnose, treat, cure, or prevent any disease or medical condition.

Use is limited to qualified professionals conducting controlled laboratory investigations in accordance with applicable institutional, regulatory, and safety requirements.

Certificate of Analysis available for applicable product batches.